Sclera reinforcement treatment and prevention of complications of progressive myopia in children
نویسنده
چکیده
We have been observing patients with progressive myopia, both adult ones and children from the age of 1 year, for 30 years. From our studies into the natural course of myopia, we have established the following age-related development patterns of chorioretinal dystrophies. Whilst central chorioretinal dystrophies (CCRD) emerge as a rule at an age of 30 or older (with the exception of cases of congenital and early acquired myopia), PVCRDs are regularly found in myopic children. PVCRDs occur in myopia several times more often than in other refraction types, while their prevalence shows a statistically significant growth with the increase of myopia degree, its progression rate, and eyeball size. These facts definitely link the emergence and development of PVCRDs with myopia progression. In progressive myopia pathogenesis, changes in structural, biochemical, and biomechanical parameters of the sclera play the leading role [6, 8]. These changes bring about the distension of the sclera in the sagittal and frontal planes.
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Scleral Cross-Linking Using Riboflavin UVA Irradiation for the Prevention of Myopia Progression in a Guinea Pig Model: Blocked Axial Extension and Altered Scleral Microstructure
PURPOSE To develop methods of collagen cross-linking (CXL) in the sclera for the treatment of progressive myopia and to investigate the biomechanical and histological changes that occur in as a result. METHODS Twenty 14-day-old guinea pigs were divided into 3 groups: the cross-linking group (CL, n = 8), non cross-linking group (NCL, n = 8), and control group (n = 4). The scleras of the right ...
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